HMB (short forβ-Hydroxy β-Methylbutyrate) is a metabolite of the the most investigated BCAA Leucine. HMB appears to be the main metabolite of leucine that effectively prevents the breakdown of muscle protein. When compared to leucine, HMB supplements appear to be significantly more potent on a gram per gram basis at reducing the rate of muscle breakdown.
HMB supplements are an extremely exciting supplement for the purpose of reducing muscle wasting during periods where muscle atrophy is accelerated, and should theoretically work to preserve muscle mass (gains) in athletes on a calorie restricted diet.
A number of scientific research studies have indicated that HMB supplementation may elicit several ergogenic benefits, including anti-catabolic, anabolic, and lipolytic effects, among others. Thus, it has been suggested that HMB may be partly responsible for the benefits of BCAA supplementation. Given that HMB is a metabolite of leucine, and can be consumed through both plant and animal foods such as grapefruit and catfish, it has been well accepted as a dietary supplement.
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