Polyene antifungal antibiotic from Streptomyces. Affinity for sterols, primarily ergosterols, of fungal cell membranes. It is used in cell culture applications to study the formation of Polyene antifungal antibiotic from Streptomyces. Affinity for sterols, primarily ergosterols, of fungal cell membranes. It is used in cell culture applications to study the formation of ion-permeable channels in fungal cell membranes. Interferes with fungal membrane permeability by forming channels in the membranes and causing small molecules to leak out. Active against yeasts also.For research use.
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